RT @TuckerGoodrich: So clearly cells can traffic in mitochondria. "Mitochondrial genome acquisition restores respiratory function and tumo…
RT @TuckerGoodrich: So clearly cells can traffic in mitochondria. "Mitochondrial genome acquisition restores respiratory function and tumo…
Transformed cells can do many things normal cells can't
So clearly cells can traffic in mitochondria. "Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA" https://t.co/5qgalvlQAI These cancer cells acquire mtDNA from the host cel
@theHumanBorch @Freewheal @gerdosi @ResearchDiets So clearly cells can traffic in mitochondria. "Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA" https://t.co/5qgalvlQAI
@S__Baksh @Caroline_Bartma @lydfinley @RJDLab @dbezwada Great group effort here! This is the first of what appears to many papers. I think the pending RCC and Lung Cancer data will make this stronger. But it fits in a paradigm where mitochondria are necess
@pastramimachine You think that's crazy? Check this from 2015 "Our findings indicate horizontal transfer of mtDNA from host cells in the tumor microenvironment to tumor cells with compromised respiratory function to re-establish respiration and tumor-init
@TommyDeeMD Growth still occurs in some of those transfer experiments, there's a suppressive effect - even that is unclear. Many cybrids are confounded by their cancer cell origin (osteosarcoma cells are very common). Some cases, recovery function might w
@naplesdave @CancerEvolves @tnseyfried Again, there is so much that contradicts this outdated narrative, I'm not sure where I'd begin https://t.co/CTObqzQ5K7
Wow. "..tumor cells with compromised respiration due to mtDNA deletion are capable of in vivo mitochondrial genome acquisition and demonstrates that mitochondrial respiration is required for tumorigenesis in these models." https://t.co/HC1WG1j15C 82/n ht
@kevinnbass @FrezzaLab My mind continues to be blown!! "tumor cells with compromised respiration due to mtDNA deletion are capable of in vivo mitochondrial genome acquisition and demonstrates that mitochondrial respiration is required for tumorigenesis in
According to Google Scholar, Our 2015 paper on mitochondrial genome acquisition has just reached citation parity with last year: https://t.co/dR4qSBEN4i The Nippo genome assembly paper has done that as well (although that's probably just shot noise): ht
@MiladMiladi_ @boas_pucker @nanopore @biorxivpreprint We also use mtDNA-free cells to investigate energy production. One thing we noticed a few years ago was that tumours don't seem to grow if they don't have mtDNA, but can pick up mtDNA from their surroun
RT @gringene_bio: Strand-consistent variant identification based on @nanopore cDNA reads. The variants are different between WT and ρ0SCL…
Strand-consistent variant identification based on @nanopore cDNA reads. The variants are different between WT and ρ0SCL cell lines because the tumour acquired cDNA from its host. This is a continuation of our mitochondrial DNA transfer experiments: https
@drjasonfung "If the mitochondrion are damaged or senescent, then cells will naturally look for other pathways." This doesn't sound like it would be consistent with [types of] cancer becoming more tumorigenic after acquisition of functional mitochondrial
Our first published article (2015) that included MinION data as a tiny component (confirmation of genetic variants) https://t.co/UKhLdY59A8
@pathogenomenick We did mitochondrial genome sequencing by PCR on the MinION a couple of years ago: https://t.co/vZhqwDgSSA
@theotherdrx Reminds me of this paper on mito-deficient tumour cells acquiring mitochondria from host. Nice. https://t.co/UKgNL0USqQ
Tan 2015 (http://t.co/I2o6pH2olB) follow-up proposes a threshold of "OXPHOS addiction" for respiration remodelling https://t.co/Vce6HckH0c
MITOCHONDRIAL DNA TRANSFERS BETWEEN CELLS A PHYSIOLOGICAL & COMMON PROCESS? / Cell Metabolism 2015 http://t.co/7fH3NLte5g
#tumor cells without #mtDNA show delayed tumor growth; tumor formation is associated with mtDNA from host, details at http://t.co/YTlSpGSG00
#Kleptochondria is the acquisition of mitochondrial DNA by lateral transfer from one cell to another http://t.co/0RerXSDcet @SFRBM #redox
#Kleptochondria is the acquisition of mitochondrial DNA by lateral transfer from one cell to another http://t.co/0RerXSDcet @SFRBM #redox
Ricky's Dictionary defines "Kleptochondria" as the lateral transfer of mitochondrial DNA from one cell to another http://t.co/0RerXSDcet
Cancer cells acquire mitochondria from surrounding cells. I've learnt something from marking a final year exam. Nice! http://t.co/2djso2stID
Cancer cells acquire mitochondria from surrounding cells. I've learnt something from marking a final year exam. Nice! http://t.co/2djso2stID
First example ever of horizontal #gene transfer, i.e. from #cell to cell, restoring #mitochondria-l function.... http://t.co/tb7LitRFvJ
Mitochondrial DNA with its 37 odd genes not to be ignored - they shuttle between cells and trigger tumor growth! http://t.co/SBhFrKndpi
For all you mitochondria lovers! This is pretty exciting! #mitochondria #science #cancer #disease http://t.co/GbXLvMPFmb
Scientists observe DNA transfer between cells for the first time! http://t.co/J9IWFX0kVR
Vengo a sacarlos de onda durísimo, denle click aquí: http://t.co/d5oVRIeH2q #PhDnini
Extraordinary mitochondrial genome transfer between cells observed: http://t.co/Y07j2wElXX and the full paper here: http://t.co/ApHzoGWXov
Extraordinary mitochondrial genome transfer between cells observed: http://t.co/Y07j2wElXX and the full paper here: http://t.co/ApHzoGWXov
Shuttling of mtDNA between host and tumor cells. http://t.co/Ki7J3uY4Nz
Extraordinary gene transfer between cells observed: mitochondrial DNA transferred into tumours http://t.co/65IftFj1fe
Nanotubular transfer of mitochondrial DNA b/w host & tumor cells restores respiration & efficacy #MalignantPlasticity http://t.co/7cFN7ehXc0
Mitochondrial Genome Acquisition Restores Respiratory Funct & Tumorigenic Potential of Cancer Cells w/out Mitoch DNA http://t.co/qsS7BsL9Jo
Wanted to procrastinate, found this instead.Evidence for horizontal mtDNA transfer between tumor cells. http://t.co/O7CZdihJdg
Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of Cancer Cells... http://t.co/MMkLv2dDep
Mitochondrial DNA transfer between tumour cells observed for the first time (!) http://t.co/953xU6qgPB http://t.co/5yxVqGxed2
Mitochondrial DNA transfer between tumour cells observed for the first time (!) http://t.co/953xU6qgPB http://t.co/5yxVqGxed2
Mitochondrial DNA transfer between tumour cells observed for the first time (!) http://t.co/953xU6qgPB http://t.co/5yxVqGxed2
Mitochondrial DNA transfer between tumour cells observed for the first time (!) http://t.co/953xU6qgPB http://t.co/5yxVqGxed2
Tumor cells deficient in mitochondrial DNA, reacquire it from micro-env't to support cell growth: http://t.co/SBwUvdJIFD. Fm @biotechbaumer
Paper of the week reveals "Tumor cells lacking mtDNA form tumors only after acquiring host mtDNA" #cancer #cellbio http://t.co/4GXoV1xnFi
Paper of the week reveals "Tumor cells lacking mtDNA form tumors only after acquiring host mtDNA" #cancer #cellbio http://t.co/4GXoV1xnFi
Mitochondrial Genome Acquisition in Cancer Cells without Mitochondrial DNA: http://t.co/haM9Jh9Bm3
@Yulian_Poe te paso los dos que he leido: -http://t.co/uUok5BiXsu -http://t.co/p7iCNWb6KB
Horizontal gene transfer among animal cells. Mitochondria might still have their own gene transfer mechanisms... http://t.co/YnXFTWHRh9
Horizontal gene transfer among animal cells. Mitochondria might still have their own gene transfer mechanisms... http://t.co/YnXFTWHRh9
Scientists observe DNA transfer between cells for the first time: submitted by Portis403 [link] [comment] http://t.co/QFki9vFVBr
Transfer mtDNA between cells propagates tumor growth. Reminiscent of bacterial conjugation(Duh, mitochondria=bacteria)http://t.co/8rLiF7rkwq
Transfer of mitochondrial DNA to tumour cells from healthy cells http://t.co/tWB9TcaCU8
Vengo a sacarlos de onda durísimo, denle click aquí: http://t.co/d5oVRIeH2q #PhDnini
“It may be that mitochondrial gene transfer between different cells is actually quite a common biological occurrence.”http://t.co/ZH6CbJ4KYD
BTW: H/T to @JustinKownacki for pointing to the mitochondrial DNA transfer paper: http://t.co/l9wYTOPYD4
Mitochondrial DNA transfer between mammalian cells? http://t.co/l9wYTOPYD4 Gotta sit down and read the paper carefully.
Scientists observe DNA transfer between cells for the first time http://t.co/jePut9SeKL http://t.co/Uadt3N9p3B
Mitochondrial Genome Acquisition Restores Respiratory Function & Tumorigenic Potential of Cancer Cells without mtDNA http://t.co/idlI8GLl3U
Mitochondrial Genome Acquisition Restores Respiratory Function & Tumorigenic Potential of Cancer Cells without mtDNA http://t.co/idlI8GLl3U
Scientists have demonstrated that a particular type of DNA can shuttle between cells ! http://t.co/aPoOFXSaMN
#mitochondrial DNA can move between cells in an animal tumor #BactoBots #ViruBots #oncolytics #cancer #oncology http://t.co/QxdVxP159g
Scientists observe DNA transfer between cells for the first time http://t.co/AhDMXjw6N6 http://t.co/EfkIis3qlA
Scientists observe DNA transfer between cells for the first time via /r/science http://t.co/2TaocYVCIW
Scientists observe DNA transfer between cells for the first time via /r/science http://t.co/h2ctQ0eN5n
http://t.co/UWEXEzX1Q6 Scientists observe DNA transfer between cells for the first time via /r/science
Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of #Cancer Cells w/o MtDNA http://t.co/xcXA2aVtcr
Scientists observe DNA transfer between cells for the first time: submitted by Portis403 [link] [comment] http://t.co/Q3p1I8QNun
Scientists observe DNA transfer between cells for the first time http://t.co/ns3LUpl4z6
Scientists observe DNA transfer between cells for the first time via /r/science http://t.co/lt7CmEEA2V #science
Scientists observe DNA transfer between cells for the first time http://t.co/x4zX8B8MeG #Science
O_o!! Hey hi pa!!l, here take this mtDNA i have a spare, go have fun! http://t.co/HMkcWqvYt6
Acqusition of mtDNA by cancer cells w/o mtDNA: http://t.co/ziViLAv42d
Destruyendo el mito de "tumores anaerobicos" (y el gran fraude de la oxigeno terapia) http://t.co/wF7UGZgu6E vía @Pako_CM_
Destruyendo el mito de "tumores anaerobicos" (y el gran fraude de la oxigeno terapia) http://t.co/wF7UGZgu6E vía @Pako_CM_
Paradigm shift? Scientists observed that mtDNA can shuttle between cells, reviving deprived tumor cells... http://t.co/Oslc9JqPQF
NOTICIA ROMPEPARADIGMA 2 DEL 2015 --> http://t.co/klZeaePXr2 EL PAPER --> http://t.co/f5ZGzbfS9i
Wow this is amazing. Tumor cells deficient in mitochondrial DNA, reacquire it from micro-env't to support cell growth http://t.co/CRRBuJtTsL
Wow this is amazing. Tumor cells deficient in mitochondrial DNA, reacquire it from micro-env't to support cell growth http://t.co/CRRBuJtTsL
Extraordinary mitochondrial genome transfer between cells observed: http://t.co/Y07j2wElXX and the full paper here: http://t.co/ApHzoGWXov
Extraordinary mitochondrial genome transfer between cells observed: http://t.co/Y07j2wElXX and the full paper here: http://t.co/ApHzoGWXov
Extraordinary mitochondrial genome transfer between cells observed: http://t.co/Y07j2wElXX and the full paper here: http://t.co/ApHzoGWXov
Extraordinary mitochondrial genome transfer between cells observed: http://t.co/Y07j2wElXX and the full paper here: http://t.co/ApHzoGWXov